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Intensive Care Med, 2008
Aström, E ; Uttman, L ; Niklason, L ; Aboab, J ; Brochard, L ; Jonson, B
Pattern of inspiratory gas delivery affects CO2 elimination in health and after acute lung injury.
J. Appl. Physiol., 2008
Devaquet, J ; Jonson, B ; Niklason, L ; Si Larbi, AG ; Uttman, L ; Aboab, J & al
Effects of inspiratory pause on CO2 elimination and arterial PCO2 in acute lung injury.
Clin Physiol Funct Imaging, 2007
Aboab, J ; Niklason, L ; Uttman, L ; Kouatchet, A ; Brochard, L ; Jonson, B
CO2 elimination at varying inspiratory pause in acute lung injury.
Intensive Care Med, 2006
Rodriguez, P ; Lellouche, F ; Aboab, J ; Buisson, CB ; Brochard, L
Transcutaneous arterial carbon dioxide pressure monitoring in critically ill adult patients.
Intensive Care Med, 2001
Van de Louw, A ; Cracco, C ; Cerf, C ; Harf, A ; Duvaldestin, P ; Lemaire, F & al
Accuracy of pulse oximetry in the intensive care unit.
Crit. Care Med., 1998
Brochard, L
Breathing: does regular mean normal?
Intensive Care Med, 1996
Roupie, EE ; Brochard, L ; Lemaire, FJ
Clinical evaluation of a continuous intra-arterial blood gas system in critically ill patients.
Chest, 1995
Lofaso, F ; Brochard, L ; Touchard, D ; Hang, T ; Harf, A ; Isabey, D
Evaluation of carbon dioxide rebreathing during pressure support ventilation with airway management system (BiPAP) devices.
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Intensive Care Med, 2015
Gibelin, A ; Parrot, A ; Maitre, B ; Brun-Buisson, C ; Mekontso Dessap, A ; Fartoukh, M & al
Acute respiratory distress syndrome mimickers lacking common risk factors of the Berlin definition.
Crit. Care Med., 2014
de Prost, N ; Melo, MF
Lung metabolism during ventilator-induced lung injury: stretching the relevance of the normally aerated lung*.
Ann Am Thorac Soc, 2014
Razazi, K ; Thille, AW ; Carteaux, G ; Beji, O ; Brun-Buisson, C ; Brochard, L & al
Effects of pleural effusion drainage on oxygenation, respiratory mechanics, and hemodynamics in mechanically ventilated patients.
Réanimation, 2013
K. Razazi;· A. Mekontso Dessap;· L. Brochard
Faut-il drainer les épanchements pleuraux liquidiens des malades ventilés ?
Intensive Care Med, 2013
Dellamonica J, Lerolle N, Sargentini C, Hubert S, Beduneau G, Di Marco F, Mercat A, Diehl JL, Richard JC, Bernardin G, Brochard L.
Effect of different seated positions on lung volume and oxygenation in acute respiratory distress syndrome.
Réanimation, 2013
T. Pham; ∙ J.C Richard; ∙ L. Brochard
Assistance par circulation extracorporelle veinoveineuse dans le traitement du syndrome de détresse respiratoire aiguë : rationnel et objectifs cliniques
Crit Care, 2013
de Prost, N ; Costa, EL ; Wellman, T ; Musch, G ; Tucci, MR ; Winkler, T & al
Effects of ventilation strategy on distribution of lung inflammatory cell activity.
Injury, 2013
Hodgson, C ; Carteaux, G ; Tuxen, DV ; Davies, AR ; Pellegrino, V ; Capellier, G & al
Hypoxaemic rescue therapies in acute respiratory distress syndrome: Why, when, what and which one?
Am. J. Respir. Crit. Care Med., 2013
Pham, T ; Combes, A ; Rozé, H ; Chevret, S ; Mercat, A ; Roch, A & al
Extracorporeal membrane oxygenation for pandemic influenza A(H1N1)-induced acute respiratory distress syndrome: a cohort study and propensity-matched analysis.
Réanimation, 2012
A. Constan, · I. Bourgeon-Ghittori, · F. Schortgen
Surveillance du patient sous ventilation mécanique invasive
Chest, 2012
Luyt, CE ; Combes, A ; Becquemin, MH ; Beigelman-Aubry, C ; Hatem, S ; Brun, AL & al
Long-term outcomes of pandemic 2009 influenza A(H1N1)-associated severe ARDS.
Am. J. Respir. Crit. Care Med., 2012
Vadász, I ; Brochard, L
Update in acute lung injury and mechanical ventilation 2011.
Crit Care, 2011
Abroug, F ; Ouanes-Besbes, L ; Dachraoui, F ; Ouanes, I ; Brochard, L
An updated study-level meta-analysis of randomised controlled trials on proning in ARDS and acute lung injury.
Am. J. Respir. Crit. Care Med., 2011
Brun-Buisson, C ; Richard, JC ; Mercat, A ; Thiébaut, AC ; Brochard, L
Early corticosteroids in severe influenza A/H1N1 pneumonia and acute respiratory distress syndrome.
Intensive Care Med, 2011
Dellamonica, J ; Lerolle, N ; Sargentini, C ; Beduneau, G ; Di Marco, F ; Mercat, A & al
PEEP-induced changes in lung volume in acute respiratory distress syndrome. Two methods to estimate alveolar recruitment.
Crit Care, 2011
Dellamonica, J ; Lerolle, N ; Sargentini, C ; Beduneau, G ; Di Marco, F ; Mercat, A & al
Accuracy and precision of end-expiratory lung-volume measurements by automated nitrogen washout/washin technique in patients with acute respiratory distress syndrome.
Am. J. Respir. Crit. Care Med., 2010
Crit. Care Med., 2010
Di Marco, F ; Devaquet, J ; Lyazidi, A ; Galia, F ; da Costa, NP ; Fumagalli, R & al,
Positive end-expiratory pressure-induced functional recruitment in patients with acute respiratory distress syndrome.
Am. J. Respir. Crit. Care Med., 2009
Brochard, L ; Rouby, JJ,
Changing mortality in acute respiratory distress syndrome? Yes, we can!
Intensive Care Med, 2008
Abroug, F ; Ouanes-Besbes, L ; Elatrous, S ; Brochard, L
The effect of prone positioning in acute respiratory distress syndrome or acute lung injury: a meta-analysis. Areas of uncertainty and recommendations for research.
Crit. Care Med., 2008
Brochard, L
Should we worry about chest wall influence on airway pressures during mechanical ventilation?
JAMA, 2008
Mercat, A ; Richard, JC ; Vielle, B ; Jaber, S ; Osman, D ; Diehl, JL & al
Positive end-expiratory pressure setting in adults with acute lung injury and acute respiratory distress syndrome: a randomized controlled trial.
Intensive Care Med, 2007
Di Marco, F ; Rota Sperti, L ; Milan, B ; Stucchi, R ; Centanni, S ; Brochard, L & al
Measurement of functional residual capacity by helium dilution during partial support ventilation: in vitro accuracy and in vivo precision of the method.
Anesthesiology, 2007
Thille, AW ; Richard, JC ; Maggiore, SM ; Ranieri, VM ; Brochard, L
Alveolar recruitment in pulmonary and extrapulmonary acute respiratory distress syndrome: comparison using pressure-volume curve or static compliance.
Intensive Care Med, 2006
Aboab, J ; Jonson, B ; Kouatchet, A ; Taille, S ; Niklason, L ; Brochard, L
Effect of inspired oxygen fraction on alveolar derecruitment in acute respiratory distress syndrome.
Intensive Care Med, 2006
Aboab, J ; Louis, B ; Jonson, B ; Brochard, L
Relation between PaO2/FIO2 ratio and FIO2: a mathematical description.
Crit Care, 2006
Brochard, L
What is a pressure-volume curve?
Intensive Care Med, 2006
Decailliot, F ; Demoule, A ; Maggiore, SM ; Jonson, B ; Duvaldestin, P ; Brochard, L
Pressure-volume curves with and without muscle paralysis in acute respiratory distress syndrome.
Intensive Care Med, 2006
Demoule, A ; Decailliot, F ; Jonson, B ; Christov, C ; Maitre, B ; Touqui, L & al
Relationship between pressure-volume curve and markers for collagen turn-over in early acute respiratory distress syndrome.
Intensive Care Med, 2006
Richard, JC ; Maggiore, SM ; Mancebo, J ; Lemaire, F ; Jonson, B ; Brochard, L
Effects of vertical positioning on gas exchange and lung volumes in acute respiratory distress syndrome.
Crit. Care Med., 2005
Ferguson, ND ; Frutos-Vivar, F ; Esteban, A ; Anzueto, A ; Alía, I ; Brower, RG & al
Airway pressures, tidal volumes, and mortality in patients with acute respiratory distress syndrome.
Intensive Care Med, 2004
Brun-Buisson, C ; Minelli, C ; Bertolini, G ; Brazzi, L ; Pimentel, J ; Lewandowski, K & al
Epidemiology and outcome of acute lung injury in European intensive care units. Results from the ALIVE study.
Am. J. Respir. Crit. Care Med., 2003
Amato, M ; Brochard, L ; Stewart, T ; Brower, R
Metaanalysis of tidal volume in ARDS.
Am. J. Respir. Crit. Care Med., 2003
Maggiore, SM ; Lellouche, F ; Pigeot, J ; Taille, S ; Deye, N ; Durrmeyer, X & al
Prevention of endotracheal suctioning-induced alveolar derecruitment in acute lung injury.
Eur Respir J Suppl, 2003
Maggiore, SM ; Richard, JC ; Brochard, L
What has been learnt from P/V curves in patients with acute lung injury/acute respiratory distress syndrome.
Crit. Care Med., 2003
Richard, JC ; Brochard, L ; Vandelet, P ; Breton, L ; Maggiore, SM ; Jonson, B & al
Respective effects of end-expiratory and end-inspiratory pressures on alveolar recruitment in acute lung injury.
Intensive Care Med, 2002
Boussarsar, M ; Thierry, G ; Jaber, S ; Roudot-Thoraval, F ; Lemaire, F ; Brochard, L
Relationship between ventilatory settings and barotrauma in the acute respiratory distress syndrome.
Intensive Care Med, 2002
Richard, JC ; Brochard, L ; Breton, L ; Aboab, J ; Vandelet, P ; Tamion, F & al
Influence of respiratory rate on gas trapping during low volume ventilation of patients with acute lung injury.
Intensive Care Med, 2002
Servillo, G ; De Robertis, E ; Maggiore, S ; Lemaire, F ; Brochard, L ; Tufano, R
The upper inflection point of the pressure-volume curve. Influence of methodology and of different modes of ventilation.
Am. J. Respir. Crit. Care Med., 2001
Brochard, L
Watching what PEEP really does.
Minerva Anestesiol, 2001
Maggiore, SM ; Brochard, L
Pressure-volume curve: methods and meaning.
Am. J. Respir. Crit. Care Med., 2001
Maggiore, SM ; Jonson, B ; Richard, JC ; Jaber, S ; Lemaire, F ; Brochard, L
Alveolar derecruitment at decremental positive end-expiratory pressure levels in acute lung injury: comparison with the lower inflection point, oxygenation, and compliance.
Eur. Respir. J., 2001
Maitre, B ; Boussat, S ; Jean, D ; Gouge, M ; Brochard, L ; Housset, B & al
Vascular endothelial growth factor synthesis in the acute phase of experimental and clinical lung injury.
Am. J. Respir. Crit. Care Med., 2001
Richard, JC ; Maggiore, SM ; Jonson, B ; Mancebo, J ; Lemaire, F ; Brochard, L
Influence of tidal volume on alveolar recruitment. Respective role of PEEP and a recruitment maneuver.
Crit. Care Med., 2000
Lemaire, F
Pressure support for the acute respiratory distress syndrome: less is more.
Intensive Care Med, 2000
Lemaire, F
ARDS and PV curves: the inseparable duet?
Anesthesiology, 2000
Mancebo, J ; Albaladejo, P ; Touchard, D ; Bak, E ; Subirana, M ; Lemaire, F & al
Airway occlusion pressure to titrate positive end-expiratory pressure in patients with dynamic hyperinflation.
Crit. Care Med., 1999
Brochard, L ; Brun-Buisson, C
Clinical trials in acute respiratory distress syndrome: what is ARDS?
Crit. Care Med., 1999
Brochard, L ; Lemaire, F
Tidal volume, positive end-expiratory pressure, and mortality in acute respiratory distress syndrome.
Am. J. Respir. Crit. Care Med., 1999
Jonson, B ; Richard, JC ; Straus, C ; Mancebo, J ; Lemaire, F ; Brochard, L
Pressure-volume curves and compliance in acute lung injury: evidence of recruitment above the lower inflection point.
Intensive Care Med, 1999
Roupie, E ; Lepage, E ; Wysocki, M ; Fagon, JY ; Chastre, J ; Dreyfuss, D & al
Prevalence, etiologies and outcome of the acute respiratory distress syndrome among hypoxemic ventilated patients. SRLF Collaborative Group on Mechanical Ventilation. Société de Réanimation de Langue Française.
J Clin Monit Comput, 1999
Svantesson, C ; Drefeldt, B ; Sigurdsson, S ; Larsson, A ; Brochard, L ; Jonson, B
A single computer-controlled mechanical insufflation allows determination of the pressure-volume relationship of the respiratory system.
Am. J. Respir. Crit. Care Med., 1998
Brochard, L ; Roudot-Thoraval, F ; Roupie, E ; Delclaux, C ; Chastre, J ; Fernandez-Mondéjar, E & al
Tidal volume reduction for prevention of ventilator-induced lung injury in acute respiratory distress syndrome. The Multicenter Trail Group on Tidal Volume reduction in ARDS.
JAMA, 1998
Brun-Buisson, C ; Brochard, L
Corticosteroid therapy in acute respiratory distress syndrome: better late than never?
Intensive Care Med, 1998
Dassieu, G ; Brochard, L ; Agudze, E ; Patkaï, J ; Janaud, JC ; Danan, C
Continuous tracheal gas insufflation enables a volume reduction strategy in hyaline membrane disease: technical aspects and clinical results.
Anesthesiology, 1997
Dambrosio, M ; Roupie, E ; Mollet, JJ ; Anglade, MC ; Vasile, N ; Lemaire, F & al
Effects of positive end-expiratory pressure and different tidal volumes on alveolar recruitment and hyperinflation.
Am. J. Physiol., 1997
Delclaux, C ; d’Ortho, MP ; Delacourt, C ; Lebargy, F ; Brun-Buisson, C ; Brochard, L & al
Gelatinases in epithelial lining fluid of patients with adult respiratory distress syndrome.
Am. J. Physiol., 1997
Delclaux, C ; Rezaiguia-Delclaux, S ; Delacourt, C ; Brun-Buisson, C ; Lafuma, C ; Harf, A Alveolar neutrophils in endotoxin-induced and bacteria-induced acute lung injury in rats.
Intensive Care Med, 1997
Servillo, G ; Roupie, E ; De Robertis, E ; Rossano, F ; Brochard, L ; Lemaire, F & al
Effects of ventilation in ventral decubitus position on respiratory mechanics in adult respiratory distress syndrome.
Intensive Care Med, 1996
Lemaire, F
The prognosis of ARDS: appropriate optimism?
Eur. Respir. J., 1995
Maitre, B ; Similowski, T ; Derenne, JP
Physical examination of the adult patient with respiratory diseases: inspection and palpation.
Am. J. Respir. Crit. Care Med., 1995
Roupie, E ; Dambrosio, M ; Servillo, G ; Mentec, H ; el Atrous, S ; Beydon, L & al
Titration of tidal volume and induced hypercapnia in acute respiratory distress syndrome.
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Chest, 2015
Mekontso Dessap, A ; Roche-Campo, F ; Launay, JM ; Charles-Nelson, A ; Katsahian, S ; Brun-Buisson, C & al
Delirium and circadian rhythm of melatonin during weaning from mechanical ventilation: An ancillary study of a weaning trial.
Crit. Care Med., 2015
Thille, AW ; Boissier, F ; Ben Ghezala, H ; Razazi, K ; Mekontso-Dessap, A ; Brun-Buisson, C
Risk factors for and prediction by caregivers of extubation failure in ICU patients: a prospective study.
Réanimation, 2014
A.W. Thille, · J.-C.M. Richard, · L. Brochard
Décision d’extubation programmée en réanimation
http://link.springer.com/article/10.1007%2Fs13546-013-0731-6
Chest, 2014
Mekontso Dessap, A ; Katsahian, S ; Roche-Campo, F ; Varet, H ; Kouatchet, A ; Tomicic, V & al
Ventilator-associated pneumonia during weaning from mechanical ventilation: role of fluid management.
JAMA, 2013
Brun-Buisson, C ; Schortgen, F
Sedation interruption for mechanically ventilated patients.
Am. J. Respir. Crit. Care Med., 2012
Mekontso Dessap, A ; Roche-Campo, F ; Kouatchet, A ; Tomicic, V ; Beduneau, G ; Sonneville, R & al
Natriuretic peptide-driven fluid management during ventilator weaning: a randomized controlled trial.
Crit. Care Med., 2011
Thille, AW ; Harrois, A ; Schortgen, F ; Brun-Buisson, C ; Brochard, L
Outcomes of extubation failure in medical intensive care unit patients.
Respir Care, 2011
Intensive Care Med, 2011
Dimassi S, Vargas F, Lyazidi A, Roche-Campo F, Dellamonica J, Brochard L.
Intrapulmonary percussive ventilation superimposed on spontaneous breathing: a physiological study in patients at risk for extubation failure.
Intensive Care Med, 2010
Cabello, B ; Thille, AW ; Roche-Campo, F ; Brochard, L ; Gómez, FJ ; Mancebo, J,
Physiological comparison of three spontaneous breathing trials in difficult-to-wean patients.
Crit. Care Med., 2009
Brochard, L ; Thille, AW,
What is the proper approach to liberating the weak from mechanical ventilation?
J. Appl. Physiol., 2009
Tobin, MJ ; Laghi, F ; Brochard, L,
Role of the respiratory muscles in acute respiratory failure of COPD: lessons from weaning failure.
Am. J. Respir. Crit. Care Med., 2006
Lellouche, F ; Mancebo, J ; Jolliet, P ; Roeseler, J ; Schortgen, F ; Dojat, M & al
A multicenter randomized trial of computer-driven protocolized weaning from mechanical ventilation.
Intensive Care Med, 2006
Mekontso-Dessap, A ; de Prost, N ; Girou, E ; Braconnier, F ; Lemaire, F ; Brun-Buisson, C & al
B-type natriuretic peptide and weaning from mechanical ventilation.
Intensive Care Med, 2005
Bouadma, L ; Lellouche, F ; Cabello, B ; Taillé, S ; Mancebo, J ; Dojat, M & al
Computer-driven management of prolonged mechanical ventilation and weaning: a pilot study.
Intensive Care Med, 2004
De Jonghe, B ; Bastuji-Garin, S ; Sharshar, T ; Outin, H ; Brochard, L
Does ICU-acquired paresis lengthen weaning from mechanical ventilation?
Am. J. Respir. Crit. Care Med., 2001
Jaber, S ; Carlucci, A ; Boussarsar, M ; Fodil, R ; Pigeot, J ; Maggiore, S & al
Helium-oxygen in the postextubation period decreases inspiratory effort.
Intensive Care Med, 2001
Am. J. Respir. Crit. Care Med., 1999
Diehl, JL ; El Atrous, S ; Touchard, D ; Lemaire, F ; Brochard, L
Changes in the work of breathing induced by tracheotomy in ventilator-dependent patients.
Am. J. Respir. Crit. Care Med., 1998
Straus, C ; Louis, B ; Isabey, D ; Lemaire, F ; Harf, A ; Brochard, L
Contribution of the endotracheal tube and the upper airway to breathing workload.
Anesthesiology, 1988
Lemaire F, Teboul JL, Cinotti L, Giotto G, Abrouk F, Steg G, Macquin-Mavier I, Zapol WM
Acute left ventricular dysfunction during unsuccessful weaning from mechanical ventilation
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Crit; Care Med., 2013
Córdoba-Izquierdo, A ; Drouot, X ; Thille, AW ; Galia, F ; Roche-Campo, F ; Schortgen, F & al
Sleep in hypercapnic critical care patients under noninvasive ventilation: conventional versus dedicated ventilators.
Crit; Care Med., 2013
Roche-Campo F, Thille AW, Drouot X, Galia F, Margarit L, Córdoba-Izquierdo A, Mancebo J, d’Ortho MP, Brochard L.
Comparison of sleep quality with mechanical versus spontaneous ventilation during weaning of critically III tracheostomized patients
Sleep Med., 2012
Drouot X, Roche-Campo F, Thille AW, Cabello B, Galia F, Margarit L, d’Ortho MP, Brochard L.
A new classification for sleep analysis in critically ill patients.
Lancet, 2010
Brochard, L,
Less sedation in intensive care: the pendulum swings back.
Sleep Med Rev, 2008
Drouot, X ; Cabello, B ; d’Ortho, MP ; Brochard, L
Sleep in the intensive care unit.
Crit. Care Med., 2008
Cabello, B ; Thille, AW ; Drouot, X ; Galia, F ; Mancebo, J ; d’Ortho, MP & al
Sleep quality in mechanically ventilated patients: comparison of three ventilatory modes.
Lancet, 2008
Brochard, L
Sedation in the intensive-care unit: good and bad?
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Crit. Care Med., 2015
Contou, D ; Coudroy, R ; Thille, AW
Acute Hypercapnic Respiratory Failure Due to Exacerbation of Chronic Obstructive Pulmonary Disease: Who Are the Patients Most at Risk for Intubation?
Eur. Respir. J., 2015
Razazi, K ; Parrot, A ; Khalil, A ; Djibre, M ; Gounant, V ; Assouad, J & al
Severe haemoptysis in patients with nonsmall cell lung carcinoma.
Intensive Care Med, 2013
Cracco, C ; Fartoukh, M ; Prodanovic, H ; Azoulay, E ; Chenivesse, C ; Lorut, C & al
Safety of performing fiberoptic bronchoscopy in critically ill hypoxemic patients with acute respiratory failure.
Lung, 2013
de Prost, N ; Parrot, A ; Cuquemelle, E ; Picard, C ; Cadranel, J
Immune diffuse alveolar hemorrhage: a retrospective assessment of a diagnostic scale.
Am J Emerg Med, 2012
Contou, D ; Razazi, K ; Katsahian, S ; Maitre, B ; Mekontso-Dessap, A ; Brun-Buisson, C & al
Small-bore catheter versus chest tube drainage for pneumothorax.
Intensive Care Med, 2012
Cecchini, J ; de Prost, N ; Mekontso-Dessap, A ; Foulet, F ; Jannière-Nartey, C ; Brun-Buisson, C & al
Life-threatening endobronchial myiasis.
Respir Med, 2012
de Prost, N ; Parrot, A ; Cuquemelle, E ; Picard, C ; Antoine, M ; Fleury-Feith, J & al
Diffuse alveolar hemorrhage in immunocompetent patients: etiologies and prognosis revisited.
Eur. Respir. J., 2010
de Prost, N ; Parrot, A ; Picard, C ; Ancel, PY ; Mayaud, C ; Fartoukh, M & al,
Diffuse alveolar haemorrhage: factors associated with in-hospital and long-term mortality.
Intensive Care Med, 2003
Baillard, C ; Boussarsar, M ; Fosse, JP ; Girou, E ; Le Toumelin, P ; Cracco, C & al
Cardiac troponin I in patients with severe exacerbation of chronic obstructive pulmonary disease.
Clin. Infect. Dis., 1999
Delclaux, C ; Zahar, JR ; Amraoui, G ; Leleu, G ; Lebargy, F ; Brochard, L & al
Corticosteroids as adjunctive therapy for severe Pneumocystis carinii pneumonia in non-human immunodeficiency virus-infected patients: retrospective study of 31 patients.
Intensive Care Med, 1996
Roupie, E ; Bouabdallah, K ; Delclaux, C ; Brun-Buisson, C ; Lemaire, F ; Vasile, N & al
Intrapleural administration of streptokinase in complicated purulent pleural effusion: a CT-guided strategy.
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Crit Care Med, 2015
Carteaux G, Córdoba-Izquierdo A, Lyazidi A, Heunks L, Thille AW, Brochard L.
Comparison Between Neurally Adjusted Ventilatory Assist and Pressure Support Ventilation Levels in Terms of Respiratory Effort.
Crit. Care Med., 2013
Carteaux, G ; Mancebo, J ; Mercat, A ; Dellamonica, J ; Richard, JC ; Aguirre-Bermeo, H & al
Bedside adjustment of proportional assist ventilation to target a predefined range of respiratory effort.
Respir Care, 2013
Maggiore, SM ; Lellouche, F ; Pignataro, C ; Girou, E ; Maitre, B ; Richard, JC & al
Decreasing the adverse effects of endotracheal suctioning during mechanical ventilation by changing practice.
Chest, 2012
Carteaux, G ; Lyazidi, A ; Cordoba-Izquierdo, A ; Vignaux, L ; Jolliet, P ; Thille, AW & al
Patient-ventilator asynchrony during noninvasive ventilation: a bench and clinical study.
Respir Care, 2012
Cuquemelle, E ; Pham, T ; Papon, JF ; Louis, B ; Danin, PE ; Brochard, L
Heated and humidified high-flow oxygen therapy reduces discomfort during hypoxemic respiratory failure.
Crit Care, 2012
Terzi, N ; Piquilloud, L ; Rozé, H ; Mercat, A ; Lofaso, F ; Delisle, S & al
Clinical review: Update on neurally adjusted ventilatory assist–report of a round-table conference.
Crit Care, 2012
Brochard, L ; Martin, GS ; Blanch, L ; Pelosi, P ; Belda, FJ ; Jubran, A & al
Clinical review: Respiratory monitoring in the ICU – a consensus of 16.
Réanimation, 2011
Carteaux G, Brochard LNouveaux modes ventilatoires: PAV+ et NAVA
Crit. Care Med., 2011
Pinto Da Costa, N ; Di Marco, F ; Lyazidi, A ; Carteaux, G ; Sarni, M ; Brochard, L
Effect of pressure support on end-expiratory lung volume and lung diffusion for carbon monoxide.
Intensive Care Med, 2010
Lyazidi, A ; Thille, AW ; Carteaux, G ; Galia, F ; Brochard, L ; Richard, JC,
Bench test evaluation of volume delivered by modern ICU ventilators during volume-controlled ventilation.
Best Pract Res Clin Anaesthesiol, 2009
Lellouche, F ; Brochard, L,
Advanced closed loops during mechanical ventilation (PAV, NAVA, ASV, SmartCare).
Chest, 2009
Lellouche, F ; Taillé, S ; Lefrançois, F ; Deye, N ; Maggiore, SM ; Jouvet, P & al,
Humidification performance of 48 passive airway humidifiers: comparison with manufacturer data.
Intensive Care Med, 2009
Thille, AW ; Lyazidi, A ; Richard, JC ; Galia, F ; Brochard, L,
A bench study of intensive-care-unit ventilators: new versus old and turbine-based versus compressed gas-based ventilators.
Intensive Care Med, 2008
Dellamonica, J ; Louis, B ; Lyazidi, A ; Vargas, F ; Brochard, L
Intrapulmonary percussive ventilation superimposed on conventional ventilation: bench study of humidity and ventilator behaviour.
Intensive Care Med, 2008
Thille, AW ; Cabello, B ; Galia, F ; Lyazidi, A ; Brochard, L
Reduction of patient-ventilator asynchrony by reducing tidal volume during pressure-support ventilation.
Intensive Care Med, 2007
Younes, M ; Brochard, L ; Grasso, S ; Kun, J ; Mancebo, J ; Ranieri, M & al
A method for monitoring and improving patient: ventilator interaction.
Respir Care, 2007
Templier, F ; Miroux, P ; Dolveck, F ; Descatha, A ; Goddet, NS ; Jeleff, C & al
Evaluation of the ventilator-user interface of 2 new advanced compact transport ventilators.
Intensive Care Med, 2006
Thille, AW ; Rodriguez, P ; Cabello, B ; Lellouche, F ; Brochard, L
Patient-ventilator asynchrony during assisted mechanical ventilation.
Intensive Care Med, 2006
Lellouche, F ; Qader, S ; Taille, S ; Lyazidi, A ; Brochard, L
Under-humidification and over-humidification during moderate induced hypothermia with usual devices.
Intensive Care Med, 2005
Jaber, S ; Delay, JM ; Matecki, S ; Sebbane, M ; Eledjam, JJ ; Brochard, L
Volume-guaranteed pressure-support ventilation facing acute changes in ventilatory demand.
Am. J. Respir. Crit. Care Med., 2004
Lellouche, F ; Taillé, S ; Maggiore, SM ; Qader, S ; L’her, E ; Deye, N & al
Influence of ambient and ventilator output temperatures on performance of heated-wire humidifiers.
Anesthesiology, 2004
Jaber, S ; Pigeot, J ; Fodil, R ; Maggiore, S ; Harf, A ; Isabey, D & al
Long-term effects of different humidification systems on endotracheal tube patency: evaluation by the acoustic reflection method.
Eur Respir J Suppl, 2003
Brochard, L
Mechanical ventilation: invasive versus noninvasive.
Am. J. Respir. Crit. Care Med., 2002
Brochard, L
When ventilator and patient’s end of inspiration don’t coincide: what’s the matter?
Intensive Care Med, 2002
Brochard, L
Intrinsic (or auto-) positive end-expiratory pressure during spontaneous or assisted ventilation.
Intensive Care Med, 2002
Brochard, L
Intrinsic (or auto-) PEEP during controlled mechanical ventilation.
Intensive Care Med, 2002
Richard, JC ; Carlucci, A ; Breton, L ; Langlais, N ; Jaber, S ; Maggiore, S & al
Bench testing of pressure support ventilation with three different generations of ventilators.
Curr Opin Crit Care, 2001
Ricard, JD ; Lemaire, F
Liquid ventilation.
Respir Care Clin N Am, 2001
Dojat, M ; Brochard, L
Knowledge-based systems for automatic ventilatory management.
Am. J. Respir. Crit. Care Med., 2000
Dojat, M ; Harf, A ; Touchard, D ; Lemaire, F ; Brochard, L
Clinical evaluation of a computer-controlled pressure support mode.
Anesthesiology, 2000
Saïssy, JM ; Boussignac, G ; Cheptel, E ; Rouvin, B ; Fontaine, D ; Bargues, L & al
Efficacy of continuous insufflation of oxygen combined with active cardiac compression-decompression during out-of-hospital cardiorespiratory arrest.
Crit. Care Med., 2000
Cook, D ; Ricard, JD ; Reeve, B ; Randall, J ; Wigg, M ; Brochard, L & al
Ventilator circuit and secretion management strategies: a Franco-Canadian survey.
Am. J. Respir. Crit. Care Med., 1998
Aslanian, P ; El Atrous, S ; Isabey, D ; Valente, E ; Corsi, D ; Harf, A & al
Effects of flow triggering on breathing effort during partial ventilatory support.
Eur. Respir. J., 1998
Lofaso, F ; Aslanian, P ; Richard, JC ; Isabey, D ; Hang, T ; Corriger, E & al
Expiratory valves used for home devices: experimental and clinical comparison.
Am. J. Respir. Crit. Care Med., 1996
Brochard, L ; Boussignac, G ; Adnot, S ; Bertrand, C ; Isabey, D ; Harf, A
Efficacy of cardiopulmonary resuscitation using intratracheal insufflation.
Am. J. Respir. Crit. Care Med., 1996
Conti, G ; Cinnella, G ; Barboni, E ; Lemaire, F ; Harf, A ; Brochard, L
Estimation of occlusion pressure during assisted ventilation in patients with intrinsic PEEP.
Am. J. Respir. Crit. Care Med., 1996
Lofaso, F ; Brochard, L ; Hang, T ; Lorino, H ; Harf, A ; Isabey, D
Home versus intensive care pressure support devices. Experimental and clinical comparison.
Am. J. Respir. Crit. Care Med., 1996
Danan, C ; Dassieu, G ; Janaud, JC ; Brochard, L
Efficacy of dead-space washout in mechanically ventilated premature newborns.
Am. J. Respir. Crit. Care Med., 1996
Dojat, M ; Harf, A ; Touchard, D ; Laforest, M ; Lemaire, F ; Brochard, L
Evaluation of a knowledge-based system providing ventilatory management and decision for extubation.
Am. J. Respir. Crit. Care Med., 1996
Cinnella, G ; Conti, G ; Lofaso, F ; Lorino, H ; Harf, A ; Lemaire, F & al
Effects of assisted ventilation on the work of breathing: volume-controlled versus pressure-controlled ventilation.
Anesthesiology, 1996
Villafane, MC ; Cinnella, G ; Lofaso, F ; Isabey, D ; Harf, A ; Lemaire, F & al
Gradual reduction of endotracheal tube diameter during mechanical ventilation via different humidification devices.
Crit. Care Med., 1996
Heyland, DK ; Cook, DJ ; King, D ; Kernerman, P ; Brun-Buisson, C
Maximizing oxygen delivery in critically ill patients: a methodologic appraisal of the evidence.
Intensive Care Med, 1996
Brochard, L
Pressure-support ventilation: still a simple mode?
Eur. Respir. J., 1996
Beydon, L ; Svantesson, C ; Brauer, K ; Lemaire, F ; Jonson, B
Respiratory mechanics in patients ventilated for critical lung disease.
Am. J. Respir. Crit. Care Med., 1995
Lessard, MR ; Lofaso, F ; Brochard, L
Expiratory muscle activity increases intrinsic positive end-expiratory pressure independently of dynamic hyperinflation in mechanically ventilated patients.
Intensive Care Med, 1995
Mancebo, J ; Amaro, P ; Mollo, JL ; Lorino, H ; Lemaire, F ; Brochard, L
Comparison of the effects of pressure support ventilation delivered by three different ventilators during weaning from mechanical ventilation.
Eur. Respir. J., 1995
Mancebo, J ; Isabey, D ; Lorino, H ; Lofaso, F ; Lemaire, F ; Brochard, L
Comparative effects of pressure support ventilation and intermittent positive pressure breathing (IPPB) in non-intubated healthy subjects.
Anesthesiology, 1991
Brochard L, Rua F, Lorino H, Lemaire F, Harf A, 1952198
Inspiratory pressure support compensates for the additional work of breathing caused by the endotracheal tube
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J. Nucl. Med., 2014
de Prost, N ; Feng, Y ; Wellman, T ; Tucci, MR ; Costa, EL ; Musch, G & al
18F-FDG kinetics parameters depend on the mechanism of injury in early experimental acute respiratory distress syndrome.
Am. J. Respir. Cell Mol. Biol., 2012
Mekontso Dessap, A ; Voiriot, G ; Zhou, T ; Marcos, E ; Dudek, SM ; Jacobson, JR & al
Conflicting physiological and genomic cardiopulmonary effects of recruitment maneuvers in murine acute lung injury.
Minerva Anestesiol, 2012
De Prost, N ; Dreyfuss, D
How to prevent ventilator-induced lung injury?
Ann Intensive Care, 2011
de Prost, N ; Ricard, JD ; Saumon, G ; Dreyfuss, D
Ventilator-induced lung injury: historical perspectives and clinical implications.
Intensive Care Med, 2011
de Prost, N ; Saumon, G ; Dreyfuss, D
Modeling the time-course of ventilator-induced lung injury: what can we learn from interspecies discrepancies?
J. Appl. Physiol., 2011
de Prost, N ; Costa, EL ; Wellman, T ; Musch, G ; Winkler, T ; Tucci, MR & al
Effects of surfactant depletion on regional pulmonary metabolic activity during mechanical ventilation.
J. Thorac. Cardiovasc. Surg., 2011
de Prost, N ; El-Karak, C ; Avila, M ; Ichinose, F ; Vidal Melo, MF
Changes in cysteinyl leukotrienes during and after cardiac surgery with cardiopulmonary bypass in patients with and without chronic obstructive pulmonary disease.
AJR Am J Roentgenol, 2010
de Prost, N ; Tucci, MR ; Melo, MF,
Assessment of lung inflammation with 18F-FDG PET during acute lung injury.
Intensice care med., 2008
de Prost N, Dreyfuss D, Ricard JD, Saumon G
Terbutaline lessens protein fluxes across the alveolo-capillary barrier during high-volume ventilation
Intensive Care Med, 2007
de Prost N, Roux D, Dreyfuss D, Ricard JD, Le Guludec D, Saumon G
Alveolar edema dispersion and alveolar protein permeability during high volume ventilation: effect of positive end-expiratory pressure
J. Appl. Physiol., 2007
de Prost N, Dreyfuss D, Saumon G
Evaluation of two-way protein fluxes across the alveolo-capillary membrane by scintigraphy in rats: effect of lung inflation.
Intensive Care Med, 2004
Schortgen, F ; Bouadma, L ; Joly-Guillou, ML ; Ricard, JD ; Dreyfuss, D ; Saumon, G
Infectious and inflammatory dissemination are affected by ventilation strategy in rats with unilateral pneumonia.
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Crit Care Med, 2015
Carteaux G, Millán-Guilarte T, De Prost N, Razazi K, Abid S, Thille AW, Schortgen F, Brochard L, Brun-Buisson C, Mekontso Dessap A.
Failure of Noninvasive Ventilation for De Novo Acute Hypoxemic Respiratory Failure: Role of Tidal Volume.
Ann Intensive Care, 2015
Contou, D ; Fragnoli, C ; Córdoba-Izquierdo, A ; Boissier, F ; Brun-Buisson, C ; Thille, AW
Severe but not mild hypercapnia affects the outcome in patients with severe cardiogenic pulmonary edema treated by non-invasive ventilation.
Intensive Care Med, 2014
Thille, AW ; Frat, JP ; Brun-Buisson, C
Trends in use and benefits of non-invasive ventilation as first-line therapy in acute respiratory failure.
Respir Care, 2014
Thille, AW ; Contou, D ; Córdoba-Izquierdo, A
Noninvasive ventilation for acute hypercapnic respiratory failure: is it the same as in hypercapnic coma?–reply.
Crit Care, 2013
Thille, AW ; Contou, D ; Fragnoli, C ; Córdoba-Izquierdo, A ; Boissier, F ; Brun-Buisson, C
Non-invasive ventilation for acute hypoxemic respiratory failure: intubation rate and risk factors.
Respir Care, 2013
Contou, D ; Fragnoli, C ; Córdoba-Izquierdo, A ; Boissier, F ; Brun-Buisson, C ; Thille, AW
Noninvasive ventilation for acute hypercapnic respiratory failure: intubation rate in an experienced unit.
Ann Intensive Care, 2012
Schortgen, F ; Follin, A ; Piccari, L ; Roche-Campo, F ; Carteaux, G ; Taillandier-Heriche, E & al
Results of noninvasive ventilation in very old patients.
Minerva Anestesiol, 2012
Sferrazza Papa, GF ; Di Marco, F ; Akoumianaki, E ; Brochard, L
Recent advances in interfaces for non-invasive ventilation: from bench studies to practical issues.
Respir Care, 2012
Lellouche, F ; Pignataro, C ; Maggiore, SM ; Girou, E ; Deye, N ; Taillé, S & al
Short-term effects of humidification devices on respiratory pattern and arterial blood gases during noninvasive ventilation.
Intensive Care Med, 2012
Vivier, E ; Mekontso Dessap, A ; Dimassi, S ; Vargas, F ; Lyazidi, A ; Thille, AW & al
Diaphragm ultrasonography to estimate the work of breathing during non-invasive ventilation.
Intensive Care Med, 2011
Fodil, R ; Lellouche, F ; Mancebo, J ; Sbirlea-Apiou, G ; Isabey, D ; Brochard, L & al
Comparison of patient-ventilator interfaces based on their computerized effective dead space.
Intensive Care Med, 2011
Roche-Campo, F ; Vignaux, L ; Galia, F ; Lyazidi, A ; Vargas, F ; Texereau, J & al
Delivery of helium–oxygen mixture during spontaneous breathing: evaluation of three high-concentration face masks.
Respir Care, 2011
Thille, AW ; Bertholon, JF ; Becquemin, MH ; Roy, M ; Lyazidi, A ; Lellouche, F & al
Aerosol delivery and humidification with the Boussignac continuous positive airway pressure device.
Crit. Care Med., 2010
Maggiore, SM ; Richard, JC ; Abroug, F ; Diehl, JL ; Antonelli, M ; Sauder, P & al,
A multicenter, randomized trial of noninvasive ventilation with helium-oxygen mixture in exacerbations of chronic obstructive lung disease.
Crit. Care Med., 2010
Roche Campo, F ; Drouot, X ; Thille, AW ; Galia, F ; Cabello, B ; d’Ortho, MP & al,
Poor sleep quality is associated with late noninvasive ventilation failure in patients with acute hypercapnic respiratory failure.
Intensive Care Med, 2010
Vignaux, L ; Tassaux, D ; Carteaux, G ; Roeseler, J ; Piquilloud, L ; Brochard, L & al,
Performance of noninvasive ventilation algorithms on ICU ventilators during pressure support: a clinical study.
Crit. Care Med., 2009
Vargas, F ; Thille, A ; Lyazidi, A ; Campo, FR ; Brochard, L,
Helmet with specific settings versus facemask for noninvasive ventilation.
Crit. Care Med., 2009
Fraticelli, AT ; Lellouche, F ; L’her, E ; Taillé, S ; Mancebo, J ; Brochard, L,
Physiological effects of different interfaces during noninvasive ventilation for acute respiratory failure.
Intensive Care Med, 2009
Lellouche, F ; Maggiore, SM ; Lyazidi, A ; Deye, N ; Taillé, S ; Brochard, L,
Water content of delivered gases during non-invasive ventilation in healthy subjects.
Intensive Care Med, 2009
Vignaux, L ; Vargas, F ; Roeseler, J ; Tassaux, D ; Thille, AW ; Kossowsky, MP & al,
Patient-ventilator asynchrony during non-invasive ventilation for acute respiratory failure: a multicenter study.
Intensive Care Med, 2006
Demoule, A ; Girou, E ; Richard, JC ; Taille, S ; Brochard, L
Benefits and risks of success or failure of noninvasive ventilation.
Intensive Care Med, 2006
Demoule, A ; Girou, E ; Richard, JC ; Taillé, S ; Brochard, L
Increased use of noninvasive ventilation in French intensive care units.
Am. J. Respir. Crit. Care Med., 2005
L’Her, E ; Deye, N ; Lellouche, F ; Taille, S ; Demoule, A ; Fraticelli, A & al
Physiologic effects of noninvasive ventilation during acute lung injury.
JAMA, 2003
Girou, E ; Brun-Buisson, C ; Taillé, S ; Lemaire, F ; Brochard, L
Secular trends in nosocomial infections and mortality associated with noninvasive ventilation in patients with exacerbation of COPD and pulmonary edema.
Eur. Respir. J., 2002
Brochard, L ; Mancebo, J ; Elliott, MW
Noninvasive ventilation for acute respiratory failure.
Intensive Care Med, 2002
Lellouche, F ; Maggiore, SM ; Deye, N ; Taillé, S ; Pigeot, J ; Harf, A & al
Effect of the humidification device on the work of breathing during noninvasive ventilation.
JAMA, 2002
Brochard, L
Noninvasive ventilation for acute respiratory failure.
Am. J. Respir. Crit. Care Med., 2001
Carlucci, A ; Richard, JC ; Wysocki, M ; Lepage, E ; Brochard, L
Noninvasive versus conventional mechanical ventilation. An epidemiologic survey.
Am. J. Respir. Crit. Care Med., 2000
Maitre, B ; Jaber, S ; Maggiore, SM ; Bergot, E ; Richard, JC ; Bakthiari, H & al
Continuous positive airway pressure during fiberoptic bronchoscopy in hypoxemic patients. A randomized double-blind study using a new device.
Am. J. Respir. Crit. Care Med., 2000
Jaber, S ; Fodil, R ; Carlucci, A ; Boussarsar, M ; Pigeot, J ; Lemaire, F & al
Noninvasive ventilation with helium-oxygen in acute exacerbations of chronic obstructive pulmonary disease.
Crit. Care Med., 2000
Brochard, L
What is really important to make noninvasive ventilation work.
JAMA, 2000
Delclaux, C ; L’Her, E ; Alberti, C ; Mancebo, J ; Abroug, F ; Conti, G & al
Treatment of acute hypoxemic nonhypercapnic respiratory insufficiency with continuous positive airway pressure delivered by a face mask: A randomized controlled trial.
JAMA, 2000
Girou, E ; Schortgen, F ; Delclaux, C ; Brun-Buisson, C ; Blot, F ; Lefort, Y & al
Association of noninvasive ventilation with nosocomial infections and survival in critically ill patients.
Thorax, 2000
Brochard, L
Non-invasive ventilation for acute exacerbations of COPD: a new standard of care.
Monaldi Arch Chest Dis, 1998
Brochard, L
Noninvasive pressure support ventilation in acute respiratory failure.
N. Engl. J. Med., 1995
Brochard, L ; Mancebo, J ; Wysocki, M ; Lofaso, F ; Conti, G ; Rauss, A & al
Noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease.
N. Engl. J. Med., 1990
Brochard L, Isabey D, Piquet J, Amaro P, Mancebo J, Messadi AA, Brun-Buisson C, Rauss A, Lemaire F, Harf A
Reversal of acute exacerbations of chronic obstructive lung disease by inspiratory assistance with a face mask
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